The usefulness of immunohistochemistry to differentiate between nasal carcinoma and lymphoma in cats: 140 cases (1986–2000)
Identifieur interne : 004579 ( Main/Exploration ); précédent : 004578; suivant : 004580The usefulness of immunohistochemistry to differentiate between nasal carcinoma and lymphoma in cats: 140 cases (1986–2000)
Auteurs : K. Nagata [États-Unis] ; M. Lamb [États-Unis] ; M. H. Goldschmidt [États-Unis] ; L. Duda [États-Unis] ; R. M. Walton [États-Unis]Source :
- Veterinary and Comparative Oncology [ 1476-5810 ] ; 2014-03.
Descripteurs français
- KwdFr :
- Animaux, Carcinomes (anatomopathologie), Carcinomes (diagnostic), Carcinomes (médecine vétérinaire), Chats, Immunohistochimie (), Immunohistochimie (médecine vétérinaire), Lymphomes (anatomopathologie), Lymphomes (diagnostic), Lymphomes (médecine vétérinaire), Maladies des chats (anatomopathologie), Maladies des chats (diagnostic), Marqueurs biologiques tumoraux, Tumeurs du nez (anatomopathologie), Tumeurs du nez (diagnostic), Tumeurs du nez (médecine vétérinaire), Études rétrospectives.
- MESH :
- anatomopathologie : Carcinomes, Lymphomes, Maladies des chats, Tumeurs du nez.
- diagnostic : Carcinomes, Lymphomes, Maladies des chats, Tumeurs du nez.
- médecine vétérinaire : Carcinomes, Immunohistochimie, Lymphomes, Tumeurs du nez.
- Animaux, Chats, Immunohistochimie, Marqueurs biologiques tumoraux, Études rétrospectives.
English descriptors
- KwdEn :
- Animals, Biomarkers, Tumor, Carcinoma (diagnosis), Carcinoma (pathology), Carcinoma (veterinary), Cat Diseases (diagnosis), Cat Diseases (pathology), Cats, Immunohistochemistry (methods), Immunohistochemistry (veterinary), Lymphoma (diagnosis), Lymphoma (pathology), Lymphoma (veterinary), Nose Neoplasms (diagnosis), Nose Neoplasms (pathology), Nose Neoplasms (veterinary), Retrospective Studies.
- MESH :
- chemical : Biomarkers, Tumor.
- diagnosis : Carcinoma, Cat Diseases, Lymphoma, Nose Neoplasms.
- methods : Immunohistochemistry.
- pathology : Carcinoma, Cat Diseases, Lymphoma, Nose Neoplasms.
- veterinary : Carcinoma, Immunohistochemistry, Lymphoma, Nose Neoplasms.
- Animals, Cats, Retrospective Studies.
Abstract
A retrospective evaluation of 232 feline nasal biopsies initially diagnosed as either carcinoma or lymphoma was performed by two pathologists. One or both pathologists disagreed with the original diagnosis in 15 cases (7%), 14 of which had original diagnoses of carcinoma. Out of the 232 cases, 140, including the disputed ones, were subjected to immunohistochemical staining with epithelial and lymphoid markers. Immunohistochemical staining of the 15 disputed cases showed that the original diagnoses were incorrect in 67% (10/15), unverified in 13% (2/15) and correct in 20% (3/15). Among the consensual diagnoses, immunohistochemistry revealed that 3% (4/125) of diagnoses were unverified because they did not stain for any of the markers evaluated. This report demonstrates the importance of immunohistochemistry in establishing a correct histologic diagnosis for nasal neoplasms in cats.
Url:
DOI: 10.1111/j.1476-5829.2012.00330.x
Affiliations:
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<term>Carcinoma (veterinary)</term>
<term>Cat Diseases (diagnosis)</term>
<term>Cat Diseases (pathology)</term>
<term>Cats</term>
<term>Immunohistochemistry (methods)</term>
<term>Immunohistochemistry (veterinary)</term>
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<term>Lymphoma (pathology)</term>
<term>Lymphoma (veterinary)</term>
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<term>Carcinomes (diagnostic)</term>
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<term>Chats</term>
<term>Immunohistochimie ()</term>
<term>Immunohistochimie (médecine vétérinaire)</term>
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<term>Tumeurs du nez</term>
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<term>Cat Diseases</term>
<term>Lymphoma</term>
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<term>Tumeurs du nez</term>
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<term>Cat Diseases</term>
<term>Lymphoma</term>
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<term>Nose Neoplasms</term>
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<front><div type="abstract">A retrospective evaluation of 232 feline nasal biopsies initially diagnosed as either carcinoma or lymphoma was performed by two pathologists. One or both pathologists disagreed with the original diagnosis in 15 cases (7%), 14 of which had original diagnoses of carcinoma. Out of the 232 cases, 140, including the disputed ones, were subjected to immunohistochemical staining with epithelial and lymphoid markers. Immunohistochemical staining of the 15 disputed cases showed that the original diagnoses were incorrect in 67% (10/15), unverified in 13% (2/15) and correct in 20% (3/15). Among the consensual diagnoses, immunohistochemistry revealed that 3% (4/125) of diagnoses were unverified because they did not stain for any of the markers evaluated. This report demonstrates the importance of immunohistochemistry in establishing a correct histologic diagnosis for nasal neoplasms in cats.</div>
</front>
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